tag:blogger.com,1999:blog-4230162007222918868.post1368903153446135553..comments2023-09-19T05:50:03.130-04:00Comments on Renal Fellow Network: The differential diagnosis of syndromes involving hypokalemia, metabolic alkalosis, and hypertensionGearoid McMahonhttp://www.blogger.com/profile/08049723797363526138noreply@blogger.comBlogger4125tag:blogger.com,1999:blog-4230162007222918868.post-59600935363462499542009-12-19T07:08:13.973-05:002009-12-19T07:08:13.973-05:00Thanks for these d/d's on your blog. They are ...Thanks for these d/d's on your blog. They are quite informative. I am linking to your postDr Sidharth Sethihttp://www.pediatric-nephrology.comnoreply@blogger.comtag:blogger.com,1999:blog-4230162007222918868.post-62697361521600219192009-12-13T19:06:38.731-05:002009-12-13T19:06:38.731-05:00we can add to the differential diagnosis of hyperm...we can add to the differential diagnosis of hypermineralocorticism with low renin low aldo , Geller syndrome wich is a gain-of-function mutation of mineralocorticoid receptor .AHhttps://www.blogger.com/profile/10183977998656631119noreply@blogger.comtag:blogger.com,1999:blog-4230162007222918868.post-17423997332671583932009-12-13T15:56:24.020-05:002009-12-13T15:56:24.020-05:00I agree with above comment.
In order to differenti...I agree with above comment.<br />In order to differentiate between Liddle's and SAME, urinary cortisol to cortisone ratio is helpful.VPatelnoreply@blogger.comtag:blogger.com,1999:blog-4230162007222918868.post-74108368164641134412009-12-13T12:44:23.064-05:002009-12-13T12:44:23.064-05:00Great review. Often a highly pimped subject among ...Great review. Often a highly pimped subject among fellows. Few corrections to the renin/aldo remarks.<br /><br />Liddle's should be low renin, low aldo. The volume expansion associated with autonomous Na reabsorption should shut off renin.<br /><br />RAS and renin-secreting tumors should be high renin, high aldo as its the aldo that is causing the volume expansion.<br /><br />Adrenal hyperfunction would be low renin, high aldo in cases of excess mineralocorticoid production. If it was due to Cushings, it would be low renin, low aldo.Anonymousnoreply@blogger.com