tag:blogger.com,1999:blog-4230162007222918868.post3442861629070051588..comments2023-09-19T05:50:03.130-04:00Comments on Renal Fellow Network: APOL1 variations associated with kidney disease in African AmericansGearoid McMahonhttp://www.blogger.com/profile/08049723797363526138noreply@blogger.comBlogger1125tag:blogger.com,1999:blog-4230162007222918868.post-68430107755320836552010-07-22T14:36:44.343-04:002010-07-22T14:36:44.343-04:00Interestingly , it is also should be noted that an...Interestingly , it is also should be noted that another paper, that was published in the same week, showed the distribution of the same APOL1 variant most associated with kidney disease risk in different African populations. It was showed that this variant is more prevalent in western compared to northeast African populations and completely absent in Ethiopia, consistent with the reported protection from forms of kidney disease known to be associated with the APOL1 variants (and also the absent of trypanosoma in Ethiopia highland).<br /><br />Tzur S, Rosset S, Shemer R, Yudkovsky G, Selig S, Tarekegn A, Bekele E, Bradman N, Wasser WG, Behar DM, Skorecki K. (Jul 2010). "Missense mutations in the APOL1 gene are highly associated with end stage kidney disease risk previously attributed to the MYH9 gene." Human Genetics.Anonymousnoreply@blogger.com