tag:blogger.com,1999:blog-4230162007222918868.post7990957846796076874..comments2023-09-19T05:50:03.130-04:00Comments on Renal Fellow Network: Rituximab in Refractory Lupus NephritisGearoid McMahonhttp://www.blogger.com/profile/08049723797363526138noreply@blogger.comBlogger7125tag:blogger.com,1999:blog-4230162007222918868.post-28035484921615394042011-09-06T21:46:50.133-04:002011-09-06T21:46:50.133-04:00I am Female 37 years and had two rounds of rituxim...I am Female 37 years and had two rounds of rituximab treatments. I am now in my 5th year of remission, medication free. At my worst I have had acute renal failure and CNS involvement.summerdawnhttps://www.blogger.com/profile/04496079838268760580noreply@blogger.comtag:blogger.com,1999:blog-4230162007222918868.post-48112102442296999152010-06-15T14:31:17.577-04:002010-06-15T14:31:17.577-04:00This drug appears to have had very good results fo...This drug appears to have had very good results for patients .. Could you please tell me where I can see the analysis of the results of the studies mentioned .. I am very interested in this informationthyroid t4 hormonehttp://www.thyroidt4.com/noreply@blogger.comtag:blogger.com,1999:blog-4230162007222918868.post-33632838692358868292010-06-15T14:30:26.246-04:002010-06-15T14:30:26.246-04:00This drug appears to have had very good results fo...This drug appears to have had very good results for patients .. Could you please tell me where I can see the analysis of the results of the studies mentioned ?.. I am very interested in this informationthyroid t4 hormonehttp://www.thyroidt4.com/noreply@blogger.comtag:blogger.com,1999:blog-4230162007222918868.post-49907100962071148022010-02-04T09:00:13.806-05:002010-02-04T09:00:13.806-05:00Great comments Francesco, thanks for the postGreat comments Francesco, thanks for the postConall O' Seaghdhahttps://www.blogger.com/profile/02591806942414088134noreply@blogger.comtag:blogger.com,1999:blog-4230162007222918868.post-36617980873322385892010-01-31T09:54:07.889-05:002010-01-31T09:54:07.889-05:00"However, positive reporting bias is a real c..."However, positive reporting bias is a real concern, and no randomized trials in renal disease exist"<br />A positive reporting bias...<br />The LUNAR trial tested RTX vs. placebo in 144 pts with class III/IV LN. RTX treatment failed to meet its efficacy end-point. Notably, pts recieved 2 RTX infusions every 6 month in addition to CS and MMF. (http://www.gene.com/gene/news/press-releases/display.do?method=detail&id=11947)<br /><br />Currently, the BELONG trial is in a recruitment phase. It will evaluate ocrelizumab in combination with CS, CYC and MMF.<br /><br />Protocol RTX administration: Should we consider safe to maintain pts at 0% or near 0% CD20 positive B cells for a long-term period?<br />Moreover, RTX may have an effect beyond B cells. What about T reg and CD20+ T (T: not a mistake) cells?Francesco Iannuzzellanoreply@blogger.comtag:blogger.com,1999:blog-4230162007222918868.post-72768535155427375012010-01-29T18:10:10.340-05:002010-01-29T18:10:10.340-05:00Yes, I forgot to mention the fact that this patien...Yes, I forgot to mention the fact that this patient was on maintenance MMF too. I'll update the post. <br />Many thanks,<br />ConallConall O' Seaghdhahttps://www.blogger.com/profile/02591806942414088134noreply@blogger.comtag:blogger.com,1999:blog-4230162007222918868.post-38199329459182821342010-01-29T17:11:42.861-05:002010-01-29T17:11:42.861-05:00I had the same dilemma after a patient achieved a ...I had the same dilemma after a patient achieved a complete response after rituxan...have you put any patients on standard maintenance therapy e.g with cellcept, after completion of rituxan txlasnabhttps://www.blogger.com/profile/12092071146263024138noreply@blogger.com