tag:blogger.com,1999:blog-4230162007222918868.post6732387166101730669..comments2023-09-19T05:50:03.130-04:00Comments on Renal Fellow Network: The use of Rituximab in Kidney DiseaseGearoid McMahonhttp://www.blogger.com/profile/08049723797363526138noreply@blogger.comBlogger4125tag:blogger.com,1999:blog-4230162007222918868.post-2545644822011578582014-09-03T19:00:19.973-04:002014-09-03T19:00:19.973-04:00Also to add to the previous comment, I am steroid ...Also to add to the previous comment, I am steroid dependant and have had very little success with treatment without steroids. This may be a positive as it has worked in steroid dependant patients before. Thanks.Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-4230162007222918868.post-48189621749754716362014-09-03T18:58:29.944-04:002014-09-03T18:58:29.944-04:00Hi I have recently been diagnosed with the above m...Hi I have recently been diagnosed with the above mentioned FSGS. Recent medications have not been working and doctors are possibly thinking on Rituximab. With side effects and openness to infection unknown I am rather worried. Is there really that little study into this drug and how it works? Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-4230162007222918868.post-70590314304797846662014-05-18T18:21:56.408-04:002014-05-18T18:21:56.408-04:00Hi Richard, thanks for the comment. Certainly my t...Hi Richard, thanks for the comment. Certainly my take on adverse events data for Rituximab is disappointingly similar to traditional agents (even CyP in RAVE & RITUXIVAS) for all cause and serious infectious events. This is surprising to me (and others) who consider Rituximab a 'clean' agent. Also a suggestion of more malignancy but I don't think the longterm data is there yet. See review ahead of print in CJASN which mentions some of this http://m.cjasn.asnjournals.org/content/early/2014/05/14/CJN.01600214Anonymoushttps://www.blogger.com/profile/08638098059713634650noreply@blogger.comtag:blogger.com,1999:blog-4230162007222918868.post-32780745056399421292014-05-18T15:47:29.647-04:002014-05-18T15:47:29.647-04:00Excellent summary guys. Rituximab's patent exp...Excellent summary guys. Rituximab's patent expires in 2015. Not sure if that will mean it becomes easier to fund trials of it's use in proteinuric kidney disease. And then there's the long term data in relation to infection and malignancy risk in the nephrology cohort. Anyone aware of any data out there looking at this? RAnonymoushttps://www.blogger.com/profile/14827805739526132137noreply@blogger.com