Wednesday, April 3, 2013

Electrolyte Disorders involving Tubular Channels

Though adult nephrologists infrequently encounter these disorders in clinic, the Board Exam loves them. Below a short table describing some of these gain- and loss-of-function channel disorders that are worth remembering. The diuretic-targeted channels are shown under parenthesis as a reference.


at

2 comments:

  1. Dr. Helbert RondonApril 4, 2013 at 9:45 AM

    Great table ! Just an observation: Autosomal Dominant Pseudohypoaldosteronism type 1 actually involves a loss of function mutation of the mineralocorticoid receptor, not of ENaC

    ReplyDelete
  2. Leonardo V Riella, MD, PhDMay 5, 2013 at 8:48 PM

    Thx Dr Rondon. There are actually two types of Pseudohypoaldo type1: AD which has a defect on aldosterone receptor and AR that has defect on ENaC.

    ReplyDelete

Renal Fellow Network encourages comments and discussion regarding the posts. Do not post any comments that are commercial or advertising in nature. Posts will be deleted if commercial or advertising comments are made. Internet users commenting on the Renal Fellow Network must post information which is true and correct to their knowledge. Sources to health/medical claims must be provided when relevant. Moderators reserve the right to erase, without notification, any comment they would judge inappropriate.