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Briefly, the authors describe placing the patient in a sitting position, and localizing the kidney via iv pyelogrophy. Then, after insertion of the needle to the marked length, vacuum suction was applied to the syringe in order to aspirate back a core of renal tissue approximately 1-2 cm in length. Using this method, the authors describe obtaining adequate biopsy tissue in 42 out of 66 patients with a minimum of bleeding complications. In this paper they also describe the ability to make diagnoses of amyloidosis, diabetic nephropathy, hypercalcemia, and chronic glomerulonephritis based on the resulting pathology.
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