These are my brackets for the eAJKD nephmadness. My winner is a number 10 seed coming out of left field. For me, the importance of the MDRD trial is that it highlighted the high prevalence of CKD in the general population, lead to the standardization of staging of CKD and raised the awareness of CKD among the non-nephrology population. Much of what we see in renal epidemiology in the last 15 years comes from the MDRD study and although the CKD-Epi equation is superseding the MDRD equation at least in research, it does not take away from the overall influence of this study.
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