Perforating
dermatoses are a group of conditions characterized by transepidermal
elimination of dermal material (collagen, elastic tissue or necrotic connective
tissue) (CMAJ). APD is one of the 4 major perforating disorders:
Image shows: Follicular keratotic papules consistent with acquired perforating dermatosis distributed diffusely over the legs (A) and buttocks (B). Skin biopsy (C) showing a hair follicle with perforation extending into the dermal tissue, which contains a tract of necrotic tissue debris with degenerate elastin fibres. (From CMAJ)
Posted by Andrew Malone
- Reactive perforating collagenosis (inherited disorder of collagen perforation)
- Elastosis perforans serpiginosa (elastic tissue perforation associated with Down syndrome and Ehler–Danlos syndrome)
- Perforating folliculitis (perforation of necrotic material secondary to local trauma)
- Acquired perforating dermatosis.
Image shows: Follicular keratotic papules consistent with acquired perforating dermatosis distributed diffusely over the legs (A) and buttocks (B). Skin biopsy (C) showing a hair follicle with perforation extending into the dermal tissue, which contains a tract of necrotic tissue debris with degenerate elastin fibres. (From CMAJ)
Posted by Andrew Malone
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